Rabbit anti Human PH domain leucine-rich repeat-containing protein phosphatase 2

Product Overview

• Article Name: Rabbit anti Human PH domain leucine-rich repeat-containing protein phosphatase 2
• Biozol Catalog Number: NMB-X2737P
• Supplier Catalog Number: X2737P
• Alternative Catalog Number: NMB-X2737P
• Manufacturer: NordicMubio
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide derived from the human PHLPP2 protein
• Alternative Names: PHLPP2, PH domain leucine-rich repeat-containing protein phosphatase 2, PH domain leucine-rich repeat-containing protein phosphatase-like, PHLPP-like

Product Description

PHLPP2 is a protein phosphatase that mediates dephosphorylation of Ser-473 of AKT1, Ser-660 of PRKCB isoform beta-II and Ser-657 of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function

Product Properties

• Concentration: See vial for concentration
• Isotype: Ig
• UniProt: Q6ZVD8
• Buffer: Provided as solution in phosphate buffered saline with 0.08% sodium azide
• Purity: Antigen Immunoaffinity Purification
• Formula: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Application Notes

• Application Notes: This antibody can be used for immunohistochemistry on formalin/paraffin sections (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.