Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking

Product Overview

• Article Name: Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
• Biozol Catalog Number: NMB-X2740P
• Supplier Catalog Number: X2740P
• Alternative Catalog Number: NMB-X2740P
• Manufacturer: NordicMubio
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide derived from the human PCSK9 protein reported to block PCSK9-LDLR interaction.
• Alternative Names: Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1

Product Description

This anitbody is made to an epitope that is reported to block the PCSK9-LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low densit

Product Properties

• Concentration: See vial for concentration
• Isotype: IgG
• UniProt: Q8NBP7
• Buffer: Provided as solution in phosphate buffered saline with 0.08% sodium azide
• Purity: Antigen Immunoaffiinity Purification
• Formula: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Application Notes

• Application Notes: Antibody can be used for Western blotting (1:400 dilution) and immunocytochemisty (2 µg/ml). Optimal concentration should be evaluated by serial dilutions.