Synthetic peptide derived from human histone H2a.x protein.
Alternative Names:
H2AFX, H2AX
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity:
Antigen Immunoaffiinity Purification
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
Antibody can be used for Western blotting (1-5 µg/ml) and immunohistochemistry (2-5 µg/ml at pH 9.5). Optimal concentration should be evaluated by serial dilutions.
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