A recombinant fragment (within amino acids 190-290) of human CD274 protein was used as the immunogen for the recombinant PD-L1 antibody.
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activate
