WM75 is a metastatic human melanoma cell line that displays pigmented morphology. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of
Concentration:
1x10 6 cells/vial (Count By Hemocytometer)
Buffer:
None
Source:
Human
Form:
Frozen Cell Suspension
Application Notes:
The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signalin
Human melanoma tumor cells with known gene mutations, disease stage, STR, and RPPA profiling
Established WM75 viable cell growth in culture using appropriate Tumor Specialized Media with 2%FBS.
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