TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 µM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 µM. TBOPP exhibits anti-tumor activity.
CAS Number:
[1996629-79-8]
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