VU-29 is a selective, positive allosteric modulator (PAM) of metabotropic glutamate 5 (mGlu5) receptor with EC50 of 9 nM and Ki of 244 nM for rmGluR5. VU-29 is selective for mGluR5 relative to other mGluR subtypes with EC50 of 557 nM, 1.5 µM and 154 nM f
CAS Number:
[890764-36-0]
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