Vicriviroc (SCH-417690, SCH-D) maleate is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5 with Ki of 2.5 nM. Vicriviroc also inhibits HIV-1 in PBMC cells, with IC90 of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (J
CAS Number:
[599179-03-0]
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