Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-beta and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophages. MRT67307 is a kinase inhibitor
Molecular Weight:
464.6
CAS Number:
[1190378-57-4]
Formula:
C26H36N6O2
Target:
IkappaB/IKK|||Autophagy
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