AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, causing mitotic delay and arresting cells in prometaphase, followed by increased apoptosis. It targets Aurora-A/-B/-C with Kd values ranging from 23-289 nM.
Molecular Weight:
442.32
CAS Number:
[2247919-28-2]
Formula:
C21H13Cl2N3O2S
Target:
PLK|||Apoptosis|||Aurora Kinase
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