ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK). Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM, EC50: 8 nM).
Molecular Weight:
481.51
CAS Number:
[2230757-47-6]
Formula:
C26H23N7O3
Target:
BTK
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