APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
Molecular Weight:
367.38
CAS Number:
[916151-99-0]
Formula:
C22H14FN5
Target:
LT-253 , LOR-253
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