SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor (IC50:1.2 nM, Kd:1.5 nM) that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by starvation or by MTOR (mechanistic ta
Molecular Weight:
443.85
CAS Number:
[1523406-39-4]
Formula:
C19H21ClF3N5O2
Target:
PI3K|||Autophagy
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