Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
Molecular Weight:
407.44
CAS Number:
[1293281-49-8]
Formula:
C21H22FN7O
Target:
OX Receptor
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