Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (sigma1) receptor (Ki = 1.14 nM) than sigma2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 µM)
Molecular Weight:
363.86
CAS Number:
[1639220-17-9]
Formula:
C19H23ClFN3O
Target:
Sigma receptor|||HER
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