Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.
Molecular Weight:
396.46
CAS Number:
[356068-94-5]
Formula:
C22H25FN4O2
Target:
VEGFR|||c-Kit|||PDGFR
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