PF-03715455 potently inhibits LPS-induced TNFalpha production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38alpha over p38beta (respective IC50: 0.88 and 23 nM). PF-037154
Molecular Weight:
700.27
CAS Number:
[1056164-52-3]
Formula:
C35H34ClN7O3S2
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