PF-3882845 also binds to the progesterone receptor (the binding IC50: 310 nM). PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2.7 nM) antagonist for hypertension and nephropathy.
Molecular Weight:
419.9
CAS Number:
[1023650-66-9]
Formula:
C24H22ClN3O2
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