PG01 is a potent CFTR Cl-channel potentiator, effective against deltaF508 (Ka 0.3 µM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 µM, 0.45 µM and 1.94 µM, respectively.PG01 increases deltaF508-CFTR Cl- currents upon addition o
Molecular Weight:
439.55
CAS Number:
[853138-65-5]
Formula:
C28H29N3O2
Target:
Phenylglycine-01
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