NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
Molecular Weight:
468.94
CAS Number:
[761437-28-9]
Formula:
C23H25ClN6O3
Target:
IGF-1R|||PYK2|||c-Met/HGFR|||FAK|||Apoptosis
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