RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively, less potent against cyclin H-CDK7 and cyclin D3-CDK6.
Molecular Weight:
545.63
CAS Number:
[784210-88-4]
Formula:
C29H35N7O4
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