Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.
Molecular Weight:
489.92
CAS Number:
[918504-65-1]
Formula:
C23H18ClF2N3O3S
Target:
RG7204 , RO5185426 , PLX4032
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