Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 µM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.
Molecular Weight:
306.75
CAS Number:
[114719-57-2]
Formula:
C18H11ClN2O
Target:
NSC 622398 , NSC622398 , Fascaplysin , NSC-622398
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