FR-167356 is a specific inhibitor of a3 isoform vacuolar type H-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.
Molecular Weight:
378.25
CAS Number:
[174185-16-1]
Formula:
C19H17Cl2NO3
Target:
FR167356 , FR 167356
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