SW106 is a selective antagonist of PTHR1-mediated cAMP signaling, not functioning as an inverse agonist on either PTHR1-T410P or PTHR1-H223R, which have activating mutations at the cytoplasmic ends of TMD helices-2 and -6, respectively.
Molecular Weight:
347.28
CAS Number:
[933452-76-7]
Formula:
C16H14F5NO2
Target:
Others
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