beta-Endorphin (1-27) is an endogenous peptide that binds to µ-, delta-, and kappa-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 n
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