Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Molecular Weight:
353.4
CAS Number:
[1015787-98-0]
Formula:
C14H19N5O4S
Target:
P2X Receptor
T5099
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