GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 µM, respectively.GNE-900 enhances DNA damage and induces apoptosis. GNE-900 has antitumor activity.
Molecular Weight:
367.45
CAS Number:
[1200126-26-6]
Formula:
C23H21N5
Target:
GNE 900 , GNE900
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