BOLD-100 free base (NKP-1339, IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded protein response (UPR), interfering
Molecular Weight:
479.15
CAS Number:
[783324-98-1]
Formula:
C14H12Cl4N4Ru
Target:
KP-1339 free base , NKP-1339 free base , NKP-1339 free base , IT-139 free base , KP-1339 free base , IT-139 free base
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