CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8, Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Molecular Weight:
251.28
CAS Number:
[2162962-69-6]
Formula:
C16H13NO2
Target:
TLR
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