DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 µM) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocytes, triggered either by chemokine
Molecular Weight:
298.72
CAS Number:
[4590-86-7]
Formula:
C16H11ClN2O2
Target:
Others
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