PV-1019 (NSC 744039) is a potent, selective inhibitor of Chk2, displaying an IC50 of 24 nM. It effectively inhibits Topotecan-induced Chk2 autophosphorylation and suppresses IR-induced apoptosis [1].
Molecular Weight:
379.37
CAS Number:
[1093793-05-5]
Formula:
C18H17N7O3
Target:
NSC 744039
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