ABD957, a potent and selective covalent inhibitor of the ABHD17 depalmitoylase family, exhibits an IC 50 value of 0.21 µM against ABHD17B. This compound effectively inhibits N-Ras signaling and suppresses the growth of NRAS-mutant AML cells.
Molecular Weight:
627.68
Formula:
C27H36F3N7O5S
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