TNG260 is a CoREST-selective deacetylase ( CoreDAC ) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3 . TNG260 leads to HDAC1 inhibition, reverses anti-PD1 resistance driven by loss of STK11. TNG260 decreases intratumoral infiltration
Molecular Weight:
383.44
Formula:
C20H18FN3O2S
* VAT and and shipping costs not included. Errors and price changes excepted