ZT55, an orally active, highly-selective JAK2 inhibitor with an IC50 of 0.031 µM, inhibits proliferation of JAK2 V617F-expressing HEL cell lines, induces apoptosis and cycle arrest, and effectively inhibits HEL xenograft tumor growth in mice models. Suit
Molecular Weight:
296.32
CAS Number:
[2138488-38-5]
Formula:
C17H16N2O3
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