N-Desethyl Sunitinib (SU-12662) (hydrochloride), a metabolite of sunitinib, is a robust ATP-competitive inhibitor of VEGFR, PDGFRbeta, and KIT, demonstrating inhibition constants (K i values) of 2, 9, 17, 8, and 4 nM for VEGFR-1, -2, -3, PDGFRbeta, and KIT, re
Molecular Weight:
406.88
Formula:
C20H24ClFN4O2
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