SS47, a PROTAC -based HPK1 degrader , exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the?in?vivo?antitumor efficacy of BCMA CAR-T cell research. HPK1, an?immunosuppressive?regulatory kinase, is a
Molecular Weight:
953.07
CAS Number:
[2636072-62-1]
Formula:
C49H56N6O12S
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