SJ1008030 (compound 8), a JAK2 PROTAC, selectively degrades JAK2. It demonstrates potent activity against MHH-CALL-4 cells, with an EC50 of 5.4 nM and an IC50 of 32.09 nM. This compound holds potential for leukemia research [1].
Molecular Weight:
873.94
CAS Number:
[2863634-96-0]
Formula:
C42H43N13O7S
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