MS9427 is a potent PROTAC EGFR degrader, demonstrating high affinity for EGFR with dissociation constants (K d s) of 7.1 nM for the wild-type (WT) EGFR and 4.3 nM for the L858R mutant EGFR, indicating selective degradation of the mutant over the WT EGFR.
Molecular Weight:
993.47
CAS Number:
[2772613-37-1]
Formula:
C48H58ClFN8O12
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