MS9449 is a potent PROTAC EGFR degrader, exhibiting dissociation constants (Kd) of 17 nM for EGFR WT and 10 nM for EGFR L858R. It effectively mediates the degradation of mutant EGFRs via both ubiquitin/proteasome system (UPS) and autophagy/lysosome pathw
Molecular Weight:
1151.82
CAS Number:
[2772612-96-9]
Formula:
C60H76ClFN10O8S
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