KTX-582 is a potent IRAK4 degrader, exhibiting DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It efficiently induces apoptosis in MYD88 MT DLBCL and has demonstrated effectiveness in inducing in vivo tumor regressions in a lymphoma model [1] [2] [3].
Molecular Weight:
872.93
CAS Number:
[2573298-13-0]
Formula:
C45H51F3N8O7
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