ITK Degrader 1, a highly selective interleukin-2-inducible T-cell kinase (ITK, DC50=3.6 nM in vivo in mice) degrader, induces rapid and prolonged degradation of ITK and effectively suppresses IL-2 secretion (EC50=35.2 nM, Jurkat cells) stimulated by anti
Molecular Weight:
943.02
Formula:
C48H57F3N10O7
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