ACBI2, an orally active and highly potent VHL PROTAC (EC 50: 7 nM), selectively degrades SMARCA2, demonstrating a DC 50 value of 1 nM in RKO cells. This compound holds potential for lung cancer research [1].
Molecular Weight:
1064.16
CAS Number:
[2913161-19-8]
Formula:
C56H68BrFN8O5S
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