Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.
Molecular Weight:
411.34
CAS Number:
[2369030-41-9]
Formula:
C21H15F6NO
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