KP-457 (TNF-alpha-converting enzyme) is a selective inhibitor of ADAM17, with an IC50 value of 11.1 nM/L in cell-free assays. The compound can also cleave a variety of molecules, including GPIbalpha, GPV and TNF-alpha.
Molecular Weight:
480.56
CAS Number:
[1365803-52-6]
Formula:
C21H24N2O7S2
Target:
TNF-alpha-converting enzyme
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