NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 µM. It disrupts the transcriptional activation of the mutated RET gene in human medullary thyroid carcinoma TT cells. The compound is utilized
Molecular Weight:
317.38
CAS Number:
[5358-76-9]
Formula:
C20H19N3O
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