TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 µM. It effectively hampers both mantGMPPNP/GPPNP and GPPNP/mantGMPPNP exchanges [1].
Molecular Weight:
498.66
CAS Number:
[2766209-50-9]
Formula:
C30H38N6O
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