MDMX/MDM2-IN-2 is a potent dual inhibitor of p53-MDM2/MDMX, demonstrating dissociation constants (Kis) of 0.23 µM for MDM2 and 2.45 µM for MDMX. It effectively disrupts the interaction between p53 and MDM2 proteins, thereby reinstating p53 functionality
Molecular Weight:
576.87
Formula:
C28H25Cl3FN3O3
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