SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in the M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK activity, this compound increases
Molecular Weight:
507.58
CAS Number:
[2927557-06-8]
Formula:
C27H31F2N7O
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