PI3Kalpha-IN-12 (compound 13), a potent and selective PI3Kalpha inhibitor (IC50: 1.2 nM), effectively suppresses HCT-116 and U87-MG cell proliferation with IC50 values of 0.83 and 1.25 µM, respectively. Intraperitoneal administration of PI3Kalpha-IN-12 (40 mg/kg) in
Molecular Weight:
726.84
Formula:
C28H36F2N10O5S3
Target:
PI3K
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